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Anti-PRMT1 Antibody

品牌
Sigma-Aldrich
货号
07-404
规格纯度
Upstate®, from rabbit
参考价格
6694.05 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The methylation of arginine is mediated by the Protein Arginine Methyl Transferase (PRMT) family of enzymes. These enzymes transfer the methyl group from S-adenosyl-Lmethionine to the guanidino nitrogen atoms of an arginine residue. Arginine methylation was found to be an important modification in signal transduction, transcription, RNA transport, and splicing. PRMT1, also known as HRMT1L2 and IR1B4, was isolated through its interaction with BTG1 and TIS21, proteins that are important in cell quiescence. PRMT1 is a 361 amino acid protein; its splicing variants differ at the N-terminus, giving rise to three isoforms of 343, 361, and 347 amino acids (variants 1, 2, and 3 respectively). Proteins involved in the metabolism of RNA are substrates for PRMT1, among them Sam68.

特异性

PRMT1 doublet

免疫原

Peptide corresponding to residues 298-318 of human protein arginine methyltransferase 1.

应用

Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function
Anti-PRMT1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of PRMT1 & has been validated in WB.

质量

routinely evaluated by immunoblot in lysates from Jurkat and 3T3/A31, NIH 3T3, HeLa, and mouse ES cells

目标描述

42-44 kDa

外形

Format: Purified
Protein A purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%

储存及稳定性

2 years at -20°C

分析说明

Control
Jurkat cell lysate

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman, mouse
manufacturer/tradenameUpstate®
technique(s)western blot: suitable
同位素/亚型IgG
NCBI登记号NM_001536 (and others)
UniProt登记号Q99873
运输wet ice
Gene Informationhuman ... PRMT1(3276)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1

Sigma-Aldrich

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