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Anti-TRXR2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500131
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Thioredoxin reductase 2 (TRXR2) is mitochondrial protein-disulfide oxidoreductase, encoded by the gene mapped to human chromosome 22q11.21. TRXR2 is one of the mammalian isoforms of thioredoxin reductase (TrxR).
Anti-TRXR2 Antibody detects endogenous levels of total TRXR2 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human TRXR2.

Immunogen Range: 471-520

生化/生理作用

Thioredoxin reductase 2 (TRXR2) regulates cell survival during mammalian embryonic development. In addition, it also regulates mitochondria-dependent apoptosis. TRXR2 also controls protein tyrosine phosphorylation and cell proliferation. The protein expression is associated with development of glioma. In humans, this enzyme stimulates the apoptosis in HeLa cells. Mutation in the gene might increase the risk of susceptibility to myocardial infarction (MI) in type 2 diabetes mellitus (T2DM) patients.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 56 kDa
species reactivityrat, mouse, human
浓度~1 mg/mL
technique(s)ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号Q9NNW7
UniProt登记号Q9NNW7
运输wet ice
储存温度−20℃
Gene Informationhuman ... TXNRD2(10587)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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