产品说明
一般描述
The IRAKM (interleukin-1 receptor-associated kinase-3) gene is mapped to human chromosome 12q14.3. This gene is predominantly expressed in monocytes and macrophages.
免疫原
IRAK-M antibody was raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M .
应用
Anti-IRAK-M antibody produced in rabbit has been used in Western blotting, immunoprecipitation and immunofluorescence.
生化/生理作用
The Irakm (interleukin-1 receptor-associated kinase-3) protein downregulates the toll like receptor (TLR)-signalling and influences the action of nuclear factor-κB (NF-κB). Increased IRAKM expression is observed in inflammatory bowel disease (IBD) and colorectal cancer. It is known to reduce the immune response against microorganism.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500193.
外形
Supplied in PBS with 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03096977 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | predicted mol wt 66 kDa |
| species reactivity | human, rat, mouse |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | AF113136 |
| UniProt登记号 | Q9Y616 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IRAK3(11213) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
