位置:首页 > 品牌 > Sigma-Aldrich >

Anti-TRB3 (N-terminal) antibody produced in rabbit

Anti-TRB-3 (N-terminal) 兔抗

品牌
Sigma-Aldrich
货号
T8076
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Tribbles homolog 3 (TRB3) gene is located on the 20p13 human chromosome. TRB3 and its related family members TRB1 and TRB2 show 45% sequence identity. It exhibits resemblance to ′tribbles′, a drosophila protein. TRB family members have a truncated kinase domain that lacks an adenosine 5′-triphosphate binding site (GXGXXG) and contain a variant catalytic core motif.

免疫原

synthetic peptide corresponding to amino acids 11-29 located near the N-terminus region of human TRB3. The immunizing sequence has limited homology (~50% identity) to mouse and rat TRB3, and has no identity to TRB1 and TRB2 isoforms.

应用

Anti-TRB3 (N-terminal) antibody produced in rabbit has been used in immunoprecipitation and immunoblotting.

生化/生理作用

Tribbles homolog 3 (TRB3) like tribbles has also been identified as a potential pro-apoptotic protein, and is induced by a variety of cell stress conditions, including hypoxia and nutrient starvation. It was previously identified as a neuronal cell death-inducible protein kinase (NIPK) that is rapidly upregulated during neuronal apoptosis. TRB3 binds to activating transcription factor 4 (ATF4) and inhibits its transcriptional activity. TRB3 has been shown to interact with mitogen-activated protein kinases (MAPK) kinases to regulate activation of MAPK pathways.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD08705525
NACRESNA.44

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 39 kDa
species reactivityhuman
增强验证recombinant expression
Learn more about Antibody Enhanced Validation
technique(s)western blot: 1-2 μg/mL using HEK-293 cells expressing human TRB3
UniProt登记号Q96RU7
运输dry ice
储存温度−20℃
Gene Informationhuman ... TRIB3(57761)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号