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Anti-Substance P Receptor Antibody, pain

品牌
Sigma-Aldrich
货号
AB5060
规格纯度
serum, Chemicon®
参考价格
6694.05 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapses. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.

特异性

Specific for the Substance P Receptor (NK-1).

免疫原

Epitope: C terminus
Synthetic peptide that corresponds to a 23 amino acid sequence (385-407) of the COOH terminus of the rat Substance P Receptor (NK-1).

应用

Research Sub Category
Neuroinflammation & Pain
Anti-Substance P Receptor Antibody, pain detects level of Substance P Receptor & has been published & validated for use in IF, IH & WB.
Immunohistochemistry:
A previous lot was used at 1:100-1:1,000 dilution.

Western Blot Analysis:
A previous lot was used at 1:500 dilution.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience

质量

Evaluated by western blot on Mouse brain membrane lysates.

Western Blot Analysis:
1:500 dilution of this antibody detected NK-1R on 10 μg of Mouse brain membrane lysates.

目标描述

35 kDa

联系

Replaces: AB5800

外形

Unpurified
Rabbit polyclonal serum containing no preservative.

储存及稳定性

Stable for 1 year at -20ºC from date of receipt.

分析说明

Control
Spinal Cord, brain membrane lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式serum
antibody product typeprimary antibodies
克隆polyclonal
species reactivitymouse, rat, guinea pig
manufacturer/tradenameChemicon®
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI登记号NM_003182.1
UniProt登记号P20366
运输dry ice
Gene Informationhuman ... TAC1(6863)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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