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Anti-INSM1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV31990
规格纯度
IgG fraction of antiserum
参考价格
5306.13 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Rabbit polyclonal anti-INSM1 antibody reacts with canine, bovine, human, mouse, rat, and zebrafish Insulinoma-associated 1 transcription factors.
Insulinoma-associated 1 (INSM1/IA-1) is a zinc-finger transcription factor restrictedly expressed in pancreatic β-cells during early pancreas development. INSM1/IA-1 regulates NeruoD1/β2 and insulin gene expression during β-cell maturation. INSM1 transcription factor, an important player in early embryonic neurogenesis, contributes to endocrine and neuroendocrine cell differentiation.

免疫原

Synthetic peptide directed towards the middle region of human INSM1

应用

Rabbit polyclonal anti-INSM1 antibody is used to tag Insulinoma-associated 1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of Insulinoma-associated 1 in endocrine and neuroendocrine cell differentiation.
Rabbit Anti-INSM1 antibody can be used for western blot assays at a concentration of 1.25μg/ml. The antibody can also be used for IHC at 4-8μg/ml using paraffin-embedded tissues.

生化/生理作用

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.

序列

Synthetic peptide located within the following region: PAAALRPPGKRPPPPTAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 53 kDa
species reactivityhuman, mouse, bovine, dog, pig
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_002187
UniProt登记号Q01101
运输wet ice
储存温度−20℃
Gene Informationhuman ... INSM1(3642)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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