Anti-IL-33 Antibody

产品说明

一般描述

IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, leading to the activation of MAP kinases and NF-kappaB. IL-33 induces production of helper T-cell type 2 (TH2) cytokines, including IL-4, IL-5 and IL-13, and is a known mediator of many inflammation responses. Cat. No. ABF108, Anti-IL-33, is an affinity purified rabbit polyclonal antibody that recognizes epitopes in the C-terminal half of murine IL-33. Reactivity to rat or other species has not been tested.

免疫原

Epitope: C-Terminal
His-tagged recombinant protein corresponding to the C-Terminal of mouse IL-33.

应用

Anti-IL-33 Antibody is an antibody against IL-33 for use in Western Blotting, Flow Cytometry.
Flow Cytometry Analysis: 0.25 µg of this antibody from a representative lot detected IL-33 in 1X10E6 monensin treated MEF1 cells.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

质量

Evaluated by Western Blotting in MEF1 cell lysate.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected IL-33 in 10 µg of MEF1 cell lysate.

目标描述

~35 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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