产品说明
一般描述
SEL1L is highly expressed in the pancreas.
SEL1L (Sel-1-like) is a type I transmembrane glycoprotein, that is located in ER (endoplasmic reticulum). It is considered as a putative tumor suppressor gene. It is located on chromosome 14q.
应用
Anti-SEL1L (N-terminal) antibody produced in rabbit has been used in
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化/生理作用
SEL1L (Sel-1-like) participates in the degradation pathway linked with endoplasmic reticulum (ER), malignant transformation and stem cells. It helps in the self regeneration of the neural stem cell. It controls cell fate developmental decision and homeostasis. It plays an important role in retaining homeostasis of endoplasmic reticulum throughout embryonic growth of vertebrate.
SEL1L is involved in cell growth and cancer progression.
外形
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~100 kDa |
| species reactivity | human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoprecipitation (IP): 2-5 μg using lysate of human MCF-7 cells indirect immunofluorescence: 2-4 μg/mL western blot: 0.5-1.0 μg/mL using whole extracts of human MCF-7 cells |
| UniProt登记号 | Q9UBV2 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SEL1L(6400) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
