产品说明
应用
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.
包装
25, 250 mg in glass bottle
生化/生理作用
The ready fluctuation of cytochrome c within the cell between ferrous and ferric states, makes it an efficient biological electron-transporter. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal catalyst of respiration, it forms the essential electron-bridge between the respirable substrates and oxygen.
制备说明
Prepared with acetic acid without using TCA.
其他说明
View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
基本信息
| EC 号 | 232-700-9 |
| MDL编号 | MFCD00130890 |
| NACRES | NA.61 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥95% based on Mol. Wt. 12,173 basis |
| 形式 | powder |
| technique(s) | cell culture | mammalian: suitable |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
