产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
ABL127 is a potent and selective inhibitor of Protein phosphatase methylesterase-1 (PME-1 or PPME-1). IC50 values were 11.1 nM and 6.4 nM in MDA-MB-231 and HEK 293T cells with no activity detected against >50 other serine hydrolases. PME-1 regulates the methylesterification state of protein phosphatase 2A (PP2A) and is implicated in cancer and neurodegeneration.
基本信息
| 经验(实验)分子式 | C17H20N2O5 |
| 分子量 | 332.35 |
| MDL编号 | MFCD28053514 |
| PubChem化学物质编号 | 329825301 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | film |
| 颜色 | colorless |
| 溶解性 | DMSO: ≥5 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | O=C1[C@](C2=CC=CC=C2)(C3CCCC3)N(C(OC)=O)N1C(OC)=O |
| InChI | 1S/C17H20N2O5/c1-23-15(21)18-14(20)17(13-10-6-7-11-13,19(18)16(22)24-2)12-8-4-3-5-9-12/h3-5,8-9,13H,6-7,10-11H2,1-2H3/t17-/m0/s1 |
| InChI key | ZRHWCAFAIHTQKD-KRWDZBQOSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
