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BGP-15

品牌
Sigma-Aldrich
货号
B4813
规格纯度
≥98% (HPLC)
参考价格
1642.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

BGP-15 is a hydroxylamine derivative, which has cytoprotective and neuroprotective properties. It reduces phospho- c-Jun N-terminal kinase (pJNK) and p38 stress signalling. BGP-15 also stimulates non-specific serine/threonine protein kinase (AKT) and insulin-like growth factor 1 receptor (IGFR1) protective signalling. BGP-15 functions as an insulin sensitizer in an olanzapine-induced metabolic disorder. It protects cells against cell death and enhances the expression of heat shock protein (HSP). BGP-15 might be used to treat heart failure (HF) and atrial fibrillation (AF).

应用

BGP-15 has been used to study its influence on proteasomal degradation of missense dystrophins.

包装

5, 25 mg in glass bottle

生化/生理作用

BGP-15 is PARP inhibitor, HSP72 activator.

基本信息

经验(实验)分子式C14H22N4O2· 2HCl
分子量351.27
MDL编号MFCD21603901
PubChem化学物质编号329773244
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
溶解性deionized water: 28 mg/mL
储存温度−20℃
SMILES stringCl.Cl.N\C(=N/OCC(O)CN1CCCCC1)c2cccnc2
InChI1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H
InChI keyISGGVCWFTPTHIX-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P264 - P270 - P301 + P310 - P405 - P501
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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