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TP-472N

品牌
Sigma-Aldrich
CAS
2080306-24-5
货号
SML1933
包装型号
规格纯度
≥98% (HPLC)
参考价格
1781.08 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

TP-472N is a negative control probe for TP-472. TP-472 is a selective probe for bromodomain-containing proteins BRD9 and BRD7. The BRD9/7 probe was developed out of a collaborative effort by Takeda and the SGC, and is of a different chemotype from BRD9/7 probes previously available. TP-472 has a KD value of 33nM for BRD9 and 340nM for BRD7 by ITC, is >30 fold selective for BRD9 over all other bromodomain family members except BRD7, and is suitable for in vivo applications. The negative control TP-472N is inactive against other bromodomains (>20μM against BRD9). For full characterization details of TP-472 and TP-472N, please visit the TP-472 probe summary on the Structural Genomics Consortium (SGC) website.

TP-472, the active BRD9/7 probe, is available from Sigma. To learn more about and purchase TP-472, click here.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

特点和优势

TP-472N is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式C19H18N2O2
分子量306.36
MDL编号MFCD30720894

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 15 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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