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sphinganine (d17:0)

品牌
Avanti
CAS
32164-02-6
货号
860654P
规格纯度
D-erythro-sphinganine (C17 base), powder
参考价格
2283.31 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Sphinganine (d17:0), also referred to as dihydrosphingosine, is devoid of double bond. Decarboxylating condensation of serine with palmitoyl-CoA yield keto intermediate(2-oxosphinganine), which is then reduced by NADPH to form Sphinganine.

应用

Sphinganine (d17:0) has been used in liquid chromatography-mass spectrometry (LC-MS) for the in-situ estimation of dihydrosphingosine utilization in N-(4-hydroxyphenyl)retinamide (4-HPR) resistant leukemia cells. It is suitable for use as an internal standard in metabolomic study.

生化/生理作用

Sphinganine (SPA) or D-erythro-sphinganine is involved in sphingolipid biosynthesis pathway. It acts as a precursor for ceramide. SPA has an ability to inhibit the activity of protein kinase c. SPA accumulation enables fumonisin B1 to stimulate apoptosis. It also has an ability to block cholesterol transport in Niemann-Pick Type C (NPC) disease.

包装

5 mL Amber Glass Screw Cap Vial (860654P-5mg)
5 mL Amber Glass Screw Cap Vial (860654P-10mg)

基本信息

经验(实验)分子式C17H37NO2
分子量287.48
NACRESNA.25

产品性质

形式powder
包装pkg of 1 × 10 mg (860654P-10mg)
pkg of 1 × 5 mg (860654P-5mg)
manufacturer/tradenameAvanti Polar Lipids 860654P
运输dry ice
储存温度−20℃
SMILES stringOC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

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