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SB265610

品牌
Sigma-Aldrich
CAS
211096-49-0
货号
SML0421
规格纯度
≥98% (HPLC)
参考价格
1503.51 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

SB265610 has been used:

  • as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR)
  • as a CX-chemokine receptor type 1 (CXCR1) inhibitor to study its effect on the chemotactic activity of chemokines on inflammatory cells
  • as a CXCR2 antagonist to study its effect on migration of neutrophils to the rat brain

包装

5, 25 mg in glass bottle

生化/生理作用

SB265610 is a potent and selective CXCR2 chemokine receptor antagonist. It has a Kd = 2.5 nM.

特点和优势

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C14H9BrN6O
分子量357.16
MDL编号MFCD09971124
PubChem化学物质编号329825416
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to light brown
溶解性DMSO: 15 mg/mL, clear
储存温度2-8℃
SMILES stringBrc1ccccc1NC(=O)Nc2ccc(C#N)c3nn[nH]c23
InChI1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
InChI keySEDUMQWZEOMXSO-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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