产品介绍：
产品说明
应用
SR144528 has been used as a cannabinoid CB2 receptor antagonist:
- to study its blocking effect on the anti-dyskinetic functionality of HU-308
- to study its effects on spontaneous excitatory postsynaptic currents (sEPSCs) from the globus pallidus neurons
- to analyze its effect on the gastric emptying in rats
包装
5, 25 mg in glass bottle
生化/生理作用
SR144528 is a potent and highly selective cannabinoid CB2 receptor inverse agonist. SR144528 exhibited a Ki of 0.6 nM at CB2 compared to 400 nM at the related CB1 receptor.
基本信息
| 经验(实验)分子式 | C29H34ClN3O |
| 分子量 | 476.05 |
| MDL编号 | MFCD05662316 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 10 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | C[C@]12[C@H](NC(C3=NN(CC4=CC=C(C)C=C4)C(C5=CC=C(Cl)C(C)=C5)=C3)=O)C(C)(C)[C@@H](C2)CC1 |
| InChI | 1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1 |
| InChI key | SUGVYNSRNKFXQM-XRHWURSXSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
