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SR144528

品牌
Sigma-Aldrich
CAS
192703-06-3
货号
SML1899
规格纯度
≥98% (HPLC)
参考价格
1538.21 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

SR144528 has been used as a cannabinoid CB2 receptor antagonist:

  • to study its blocking effect on the anti-dyskinetic functionality of HU-308
  • to study its effects on spontaneous excitatory postsynaptic currents (sEPSCs) from the globus pallidus neurons
  • to analyze its effect on the gastric emptying in rats

包装

5, 25 mg in glass bottle

生化/生理作用

SR144528 is a potent and highly selective cannabinoid CB2 receptor inverse agonist. SR144528 exhibited a Ki of 0.6 nM at CB2 compared to 400 nM at the related CB1 receptor.

基本信息

经验(实验)分子式C29H34ClN3O
分子量476.05
MDL编号MFCD05662316
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear
储存温度−20℃
SMILES stringC[C@]12[C@H](NC(C3=NN(CC4=CC=C(C)C=C4)C(C5=CC=C(Cl)C(C)=C5)=C3)=O)C(C)(C)[C@@H](C2)CC1
InChI1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
InChI keySUGVYNSRNKFXQM-XRHWURSXSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

Sigma-Aldrich

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