产品介绍：
产品说明
应用
SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6
生化/生理作用
SB 205384 is a selective and positive allosteric modulator of non-benzodiazepine site of the GABAA receptor.3 It affects the extrasynaptic GABAA receptors in rat cortical neurons4 and enhances the GABAergic transmission onto pro-opiomelanocortin neurons in mice.5
GABAA receptor modulator selective for the α3β2γ2 subunit combination.
法律信息
Manufactured and sold under license from GlaxoSmithKline Pharmaceuticals
基本信息
| 经验(实验)分子式 | C17H18N2O3S |
| 分子量 | 330.40 |
| MDL编号 | MFCD00918851 |
| PubChem化学物质编号 | 24278711 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 形式 | solid |
| 颜色 | off-white |
| 溶解性 | DMSO: 18 mg/mL H2O: insoluble |
| SMILES string | CC#CCOC(=O)c1c(C)nc2sc3CC(O)CCc3c2c1N |
| InChI | 1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19) |
| InChI key | JDTZAGLGBRRCJT-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
