产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
PF-956980 is a FGF1 receptor antagonist; PDGF receptor modulator; Flt3 tyrosine kinase modulator; and VEGF antagonist.
特点和优势
This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
其他说明
This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
经验(实验)分子式 | C18H26N6O · xH2O |
分子量 | 342.44 (anhydrous basis) |
MDL编号 | MFCD18452852 |
PubChem化学物质编号 | 329823736 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
旋光性 | [α]/D +33 to +40°, c = 0.5 in methanol |
manufacturer/tradename | Pfizer® |
颜色 | white to off-white |
溶解性 | DMSO: ≥50 mg/mL |
创始人 | Pfizer |
储存温度 | 2-8℃ |
SMILES string | O.C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)N4CCCC4 |
InChI | 1S/C18H26N6O.H2O/c1-13-6-10-24(18(25)23-8-3-4-9-23)11-15(13)22(2)17-14-5-7-19-16(14)20-12-21-17;/h5,7,12-13,15H,3-4,6,8-11H2,1-2H3,(H,19,20,21);1H2/t13-,15+;/m1./s1 |
InChI key | VZUKSTKLTSSYKP-PBCQUBLHSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 + H311 + H331 |
预防措施声明 | P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 |
危险分类 | Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral |
储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |