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Mephetyl tetrazole

品牌
Sigma-Aldrich
CAS
916923-10-9
货号
M7945
规格纯度
≥98% (HPLC), oil
参考价格
2174.31 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C20H22N4O
分子量334.41
MDL编号MFCD11045297
PubChem化学物质编号329818044
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式oil
颜色pale yellow
溶解性DMSO: >5 mg/mL
储存温度2-8℃
SMILES stringCOc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1
InChI1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
InChI keyVREPWWBWXVLSEF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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