产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Gomisin A guards against hepatic and renal injury stimulated by CCl(4) (carbon tetrachloride) exposure by differential modulation of the mitogen-activated protein kinases (MAPK) signal transduction pathway. It also blocks inflammatory responses, promoted by lipopolysaccharide in N9 microglia by blocking the NF-κB (nuclear factor kappa light chain enhancer of activated B cells)/MAPKs pathway.
Gomisin A is a major dibenzocyclooctadiene lignan from medicinal plant Schizandra Chinese that exhibit a wide variety of interesting biological activities, including hepatoprotective, antiviral, anticancer, neuroprotective and anti-inflammatory. Gomisin A suppressed the expressions of iNOS and COX-2 in LPS-stimulated N9 microglia through suppression of NF-κB/MAPKs pathway.
基本信息
| 经验(实验)分子式 | C23H28O7 |
| 分子量 | 416.46 |
| PubChem化学物质编号 | 329825744 |
| NACRES | NA.77 |
产品性质
| 生物来源 | Schisandra chinensis |
| 质量水平 | 100 |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 20 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | C[C@]1([H])[C@@](C)(O)CC2=C(C(OC)=C(OC)C(OC)=C2)C3=C(OC)C4=C(OCO4)C=C3C1 |
| InChI | 1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3/t12-,23-/m0/s1 |
| InChI key | ZWRRJEICIPUPHZ-MYODQAERSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
