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BAY-784

(2S)-N-[[3-Chloro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-cyclopropyl-1-(4-fluorophenyl)sulfonyl-1′,1′-dioxo-spiro[indoline-3,4′-thiane]-5-carboxamide

品牌
Sigma-Aldrich
CAS
1631164-24-3
货号
SML3025
规格纯度
≥98% (HPLC)
参考价格
1272.2 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

BAY-784 is an orally available, non-toxic, potent, and selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R], which is potently active in other species including rate, dogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.

基本信息

经验(实验)分子式C29H26ClF4N3O5S2
分子量672.11

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
旋光性[α]/D -120 to -100°, c = 0.5 in chloroform-d
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringO=S(CCC1(C2=C(N3S(C4=CC=C(F)C=C4)(=O)=O)C=CC(C(NCC5=C(Cl)C=C(C(F)(F)F)C=N5)=O)=C2)[C@@H]3C6CC6)(CC1)=O

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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