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AEG 3482

品牌
Sigma-Aldrich
CAS
63735-71-7
货号
SML0264
包装型号
规格纯度
≥98% (HPLC)
参考价格
1225.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous inhibitor of c-Jun N-terminal kinase (JNK) activity. Treatment of PC12 cells with AEF3284 blocks JNK dependent apoptosis.
AEG 3482 is an imidazothiadiazole sulfonamide of 281 D with an anti-apoptotic property.

特点和优势

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C10H8N4O2S2
分子量280.33
MDL编号MFCD02064987
PubChem化学物质编号329825272
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色faintly yellow to dark yellow
溶解性DMSO: ≥15 mg/mL
储存温度2-8℃
SMILES stringNS(=O)(=O)c1nn2cc(nc2s1)-c3ccccc3
InChI1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16)
InChI keyMQUYTXDAVCOCMX-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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