产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Begacestat (GSI-953) is a selective γ-secretase inhibitor that selectively inhibits cleavage of APP over Notch.
其他说明
This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
| 经验(实验)分子式 | C9H8ClF6NO3S2 |
| 分子量 | 391.74 |
| MDL编号 | MFCD18782675 |
| PubChem化学物质编号 | 329823761 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| manufacturer/tradename | Pfizer® |
| 颜色 | white to tan |
| 溶解性 | DMSO: ≥15 mg/mL |
| 创始人 | Pfizer |
| 储存温度 | 2-8℃ |
| SMILES string | OC[C@@H](NS(=O)(=O)c1ccc(Cl)s1)C(C(F)(F)F)C(F)(F)F |
| InChI | 1S/C9H8ClF6NO3S2/c10-5-1-2-6(21-5)22(19,20)17-4(3-18)7(8(11,12)13)9(14,15)16/h1-2,4,7,17-18H,3H2/t4-/m1/s1 |
| InChI key | PSXOKXJMVRSARX-SCSAIBSYSA-N |
| Gene Information | human ... APH1A(51107), APH1B(83464), NCSTN(23385), PSEN1(5663), PSEN2(5664), PSENEN(55851) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
