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(R,S)-AM1241

品牌
Sigma-Aldrich
CAS
444912-48-5
货号
A6478
规格纯度
≥98% (HPLC), solid
参考价格
3087.98 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

(R,S)-AM1241 has been used as a cannabinoid CB2 agonist:

  • to study its inhibitory effect on bone cancer-induced pain and bone loss
  • to study the effect of its interaction with 17βestradiol on proliferation activity in primary human osteoblasts
  • to evaluate the sites of CB2 mediated antinociception in vivo.

包装

5, 25 mg in glass bottle

生化/生理作用

AM1241 acts as an antinociceptive agent in several animal pain models. It has a potential to delay disease progression in amyotrophic lateral sclerosis (ALS) mouse model. Intrathecal, intravenous or intraperitoneal administration of AM1241 reduces hyperalgesia and allodynia in neuropathic rats.
Selective CB2 cannabinoid receptor agonist

基本信息

经验(实验)分子式C22H22IN3O3
分子量503.33
MDL编号MFCD11045986
PubChem化学物质编号24891092
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
drug controlregulated under CDSA - not available from sigma-aldrich Canada
颜色 yellow
溶解性DMSO: ~18 mg/mL at 60 ℃
SMILES stringCN1CCCCC1Cn2cc(C(=O)c3cc(ccc3I)[N+]([O-])=O)c4ccccc24
InChI1S/C22H22IN3O3/c1-24-11-5-4-6-16(24)13-25-14-19(17-7-2-3-8-21(17)25)22(27)18-12-15(26(28)29)9-10-20(18)23/h2-3,7-10,12,14,16H,4-6,11,13H2,1H3
InChI keyZUHIXXCLLBMBDW-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H319 - H334 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Sigma-Aldrich

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