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T3MG

品牌
Sigma-Aldrich
CAS
63088-04-0
货号
T2455
包装型号
规格纯度
参考价格
2054.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

T3MG is a selective inhibitor of excitatory amino acid transporters GLT-1, EAAT2, and EAAT4. T3MG has long been utilized as a gold standard in the study of general EAAT function. It has more recently been shown to be selective for EAAT2 and EAAT4 as compared to EAAT1 and EAAT3 in electrophysiology and glutamate/aspartate uptake assays. Although there are other EAAT2-selective compounds, this is the first tool with selectivity for EAAT4. T3MG is not a substrate for the transporters themselves, nor does it have activity at glutamate ion channels.

特点和优势

This compound is featured on the Excitatory Amino Acid Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

制备说明

T3MG dissolves in water at a concentration that is greater than 1.5 mg/ml.

基本信息

经验(实验)分子式C6H11NO4
分子量161.16
MDL编号MFCD09836097
PubChem化学物质编号329826708
NACRESNA.77

产品性质

测定 (single spot, TLC)
质量水平100
形式powder
颜色 white to off-white
溶解性H2O: >1.5 mg/dL
储存温度room temp
SMILES stringC[C@@H](CC(O)=O)[C@@H](N)C(O)=O
InChI1S/C6H11NO4/c1-3(2-4(8)9)5(7)6(10)11/h3,5H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,5+/m0/s1
InChI keyFHJNAFIJPFGZRI-WVZVXSGGSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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