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Sulfameter

磺胺对甲氧嘧啶

品牌
Sigma-Aldrich
CAS
651-06-9
货号
S0383
包装型号
规格纯度
参考价格
1086.53 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Chemical structure: sulfonamide

应用

Sulfameter is a sulfonamide antibiotic used as a leprostatic agent and to treat urinary tract infections. It has been investigated as a potential therapy for chloroquine-resistant malaria during pregnancy.

包装

5 g in poly bottle

生化/生理作用

Sulfameter is a sulfonamide antibiotic. Sulfonamides block the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfonamides are competitive inhibitors of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. Sulfameter is a dihydrofolate reductase (DHFR) inhibitor. Sulfonamides are active against Gram positive bacteria and Gram negative bacteria. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

基本信息

经验(实验)分子式C11H12N4O3S
分子量280.30
Beilstein621130
EC 号211-480-8
MDL编号MFCD00006067
PubChem化学物质编号24899422
NACRESNA.85

产品性质

质量水平200
形式powder
储存条件 (Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)
颜色 white to faint yellow
作用机制enzyme | inhibits
抗生素抗菌谱Gram-negative bacteria
Gram-positive bacteria
mycobacteria
parasites
储存温度2-8℃
SMILES stringCOc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1
InChI1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
InChI keyGPTONYMQFTZPKC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

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