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SB-204070 hydrochloride

品牌
Sigma-Aldrich
CAS
148702-58-3
货号
S3313
规格纯度
solid, ≥97% (HPLC)
参考价格
8428.11 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.

包装

5, 25 mg in glass bottle

生化/生理作用

SB-204070 is a highly potent and specific antagonist of 4-HT4 receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.
Selective 5-HT4 serotonin receptor antagonist.

法律信息

Manufactured and sold under exclusive license from GlaxoSmithKline Pharmaceuticals

基本信息

经验(实验)分子式C19H27ClN2O4 · HCl
分子量419.34
MDL编号MFCD03453014
PubChem化学物质编号24278704
NACRESNA.77

产品性质

质量水平100
测定≥97% (HPLC)
形式solid
mp243-245 ℃ (lit.)
溶解性H2O: 20 mg/mL (with heating)
SMILES stringCl[H].CCCCN1CCC(CC1)COC(=O)c2cc(Cl)c(N)c3OCCOc23
InChI1S/C19H27ClN2O4.ClH/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18;/h11,13H,2-10,12,21H2,1H3;1H
InChI keyYEQGKAOSYSXEPU-UHFFFAOYSA-N
Gene Informationhuman ... HTR4(3360)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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