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LM11A-31 dihydrochloride

品牌
Sigma-Aldrich
CAS
1214672-15-7
货号
SML0664
规格纯度
≥95% (HPLC)
参考价格
702.02 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

LM11A-31 dihydrochloride has been used to study the effect of p75 neurotrophin receptor (p75 NTR) blockade, by non-peptide LM11A-31 ligand, on PC12 cell viability.

包装

5, 25 mg in glass bottle

生化/生理作用

LM11A-31 is a non-peptide ligand of the p75 neurotrophin receptor (p75NTR). LM11A-31 blocks pro-NGF induced cell death in neuronal cultures, and protects neuronal cells from the the cytotoxic effects of cisplatin or methotrexate. Oral administration of LM11A-31 promotes the survival of oligodendrocytes and myelinated axons in a mouse spinal cord injury model and improves function in both weight-bearing and non-weight bearing tests.

基本信息

经验(实验)分子式C12H25N3O2 · 2HCl
分子量316.27
MDL编号MFCD11505486
PubChem化学物质编号329825578
NACRESNA.77

产品性质

质量水平100
测定≥95% (HPLC)
形式oil
储存条件desiccated
颜色 colorless to yellow
储存温度2-8℃
SMILES stringCl.Cl.CCC(C)C(N)C(=O)NCCN1CCOCC1
InChI1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H
InChI keyLLIHJRRZJDEKLB-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H319 - H335 - H410
预防措施声明P273 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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