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Longdaysin

品牌
Sigma-Aldrich
货号
SML0127
规格纯度
≥98% (HPLC)
参考价格
1698.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

包装

5, 25 mg in glass bottle

生化/生理作用

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

基本信息

经验(实验)分子式C16H16F3N5
分子量335.33
MDL编号MFCD20527323
PubChem化学物质编号329825177

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥15 mg/mL
储存温度2-8℃
SMILES stringCC(C)N(C=N1)C2=C1C(NCC3=CC(C(F)(F)F)=CC=C3)=NC=N2
InChI1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22)
InChI keyREKSFCCYDQMSIN-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 - H315 - H319 - H335 - H361d
预防措施声明P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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