产品说明
应用
IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).
包装
5, 25 mg in glass bottle
生化/生理作用
IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.
IMM-01 binds and activates formin thereby leading to autoinhinition.
基本信息
经验(实验)分子式 | C12H17N3O2S |
分子量 | 267.35 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to light brown |
溶解性 | DMSO: 10 mg/mL, clear |
储存温度 | 2-8℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |