产品说明
应用
I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
包装
5 mg in glass bottle
生化/生理作用
Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
特点和优势
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制备说明
I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.
基本信息
经验(实验)分子式 | C17H12INO5 |
分子量 | 437.19 |
MDL编号 | MFCD03453582 |
PubChem化学物质编号 | 24278758 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
形式 | solid |
溶解性 | DMSO: 50 mg/mL |
储存温度 | −20℃ |
SMILES string | COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2 |
InChI | 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+ |
InChI key | HSRMHXWCTRFVHK-NYYWCZLTSA-N |
Gene Information | human ... IGF1(3479), IGF1R(3480) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |