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Enalaprilat Dihydrate

依那普利 二水合物

品牌
Sigma-Aldrich
CAS
84680-54-6
货号
E9658
规格纯度
≥98% (HPLC)
参考价格
1649.92 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Enalapril, the ethyl ester of enalaprilat exhibits slight pharmacological activity until it is hydrolyzed in the liver to enalaprilat. Enalaprilat, a IV form of an angiotensin-converting-enzyme inhibitor (ACE) prevents the transformation of angiotensin I to angiotensin II, a potent vasoconstrictor.
Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Angiotensin Receptors and Bradykinin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C18H24N2O5 ·2H2O
分子量384.42
EC 号278-459-3
MDL编号MFCD00941393
PubChem化学物质编号329799089
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
溶解性H2O: 14 mg/mL at 60 ℃ (warming for 5 minutes)
DMSO: 64 mg/mL
创始人Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度room temp
SMILES stringO.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI keyMZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Informationhuman ... ACE(1636)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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