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EF5

品牌
Sigma-Aldrich
CAS
152721-37-4
货号
SML1961
规格纯度
≥98% (HPLC)
参考价格
1531.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

EF5 is a 2-nitroimidazole-based hypoxia marker corresponding to a pentafluorinated derivative of the hypoxic cell-radiation sensitizer etanidazole. Under low oxygen (hypoxic) condition, reductive activation of its 2-nitroimidazole moiety leads to enhanced EF5 adduct formation with protein thiols and reduced glutathione. The pentafluorination derivatization substantially decreases the proportion of low molecular weight hydrolytic fragmentation of the adducts, making EF5 superior to etanidazole when utilized as a hypoxia marker by immunohistological staining.

基本信息

经验(实验)分子式C8H7F5N4O3
分子量302.16
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(NCC(F)(F)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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