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BLT-1

品牌
Sigma-Aldrich
CAS
321673-30-7
货号
SML0059
规格纯度
≥98% (HPLC)
参考价格
1633.58 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux.
BLT-1 (Block lipid transport-1) has been used as an inhibitor of the SR-BI (scavenger receptor, class B, type I) mediated lipid transfer to determine if miR-223-3p export from polymorphonuclear neutrophils (PMNs) to high-density lipoproteins (HDLs) is dependent on SR-BI-mediated lipid flux. It has also been used as a SR-BI inhibitor to study the effect of HDL on osteocalcin (OCN) expression in monocyte cell lines through SR-B1.

包装

5, 25 mg in glass bottle

生化/生理作用

Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL.

基本信息

经验(实验)分子式C12H23N3S
分子量241.40
MDL编号MFCD00571007
PubChem化学物质编号329825125
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥13 mg/mL
储存温度2-8℃
SMILES stringCCCCCCC1CCC\C1=N/NC(N)=S
InChI1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+
InChI keyOWGUSBISUVLUJF-SDNWHVSQSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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