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Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse

品牌
Sigma-Aldrich
货号
I4028
规格纯度
clone 70625.111, purified immunoglobulin, lyophilized powder
参考价格
4915.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The antibody will neutralize the biological activity of recombinant human IL-18 receptor.

免疫原

recombinant human IL-18 receptor extracellular domain, expressed in NS0 cells.

生化/生理作用

IL-18 belongs to the IL-1 cytokine superfamily and is a regulator of innate and acquired immune responses. The immune responses of IL-18 are mediated by its interaction and subsequent signaling by IL-18 receptor complex. The IL-18R complex is made up of α chain that binds to extracellular IL-18 and a β chain that is involved in signal transduction. The IL-18/IL-18R signaling enhances T and NK cell maturation, cytotoxicity and secretion of cytokines.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

制备说明

Purified using protein G.

基本信息

MDL编号MFCD02096767
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆70625.111, monoclonal
形式lyophilized powder
species reactivityhuman
technique(s)flow cytometry: suitable (2.5μg/SUP>106 cell)
immunocytochemistry: 8-25 μg/mL
immunohistochemistry: 8-25 μg/mL
同位素/亚型IgG1
UniProt登记号Q13478
储存温度−20℃
Gene Informationhuman ... IL18R1(8809)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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