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p-APMSF, Hydrochloride-CAS 74938-88-8-Calbiochem

品牌
Sigma-Aldrich
CAS
74938-88-8
货号
178281
规格纯度
Alternative to DFP and PMSF.
参考价格
2165.23 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Alternative to DFP and PMSF. An irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentration. Acts on C1r, C1s, Factor Xa, and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF.
An alternative to DFP and PMSF. Specific irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentrations. Acts on C1r, C1s, Factor Xa and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF. Stability is pH dependent: t½ = 20 min at pH 6.0; 6 min at pH 7.0; 1 millisecond at pH 8.0.

包装

5 mg in Plastic ampoule

生化/生理作用

Primary Target
trypsin-like serine proteases
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Unstable in solution; reconstitute just prior to use.

其他说明

Cole, T.C., et al. 1989. Biochim. Biophys. Acta 990, 254.
Laura, R., et al. 1980. Biochemistry19, 4859.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

MDL编号MFCD00078902

产品性质

质量水平100
测定≥97% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated
颜色 white
溶解性water: 25 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H
InChI keyKHLLRHIUKOJXLL-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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