产品说明
一般描述
Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
包装
5 μg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
MMP-1
Cell permeable: no
警告
Toxicity: Standard Handling (A)
外形
In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
制备说明
Prepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
其他说明
Greene, J., et al. 1996. J. Biol. Chem. 271, 30375.
Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
法律信息
Brij is a registered trademark of Croda International PLC
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
| 质量水平 | 100 |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | liquid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze avoid repeated freeze/thaw cycles |
| 运输 | wet ice |
| 储存温度 | −70℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
