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BEC, Hydrochloride-Calbiochem

品牌
Sigma-Aldrich
货号
197900
规格纯度
A boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginases I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5).
参考价格
3562.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

A boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginases I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5). BEC does not inhibit nitric oxide synthase (NOS). Causes significant enhancement of NO-dependent smooth muscle relaxation in human penile corpus cavernosum tissue.
A boronic acid based arginine analog that acts as a selective, slow- binding, reversible, competitive transition state inhibitor of arginase type I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5). Shown to enhance nitric oxide-dependent relaxation of human penile corpus cavernosum smooth muscle by inhibiting the activity of arginase. Does not inhibit the activity of nitric oxide synthase (NOS) and may serve as a valuable reagent to probe the physiological relationship between arginase and NOS.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Target Ki: 310 nM for human recombinant type II arginase, pH 7.5
Cell permeable: no
Primary Target
arginase 1, arginase 2

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot, flush with nitrogen, and freeze at -20°C. Stock solutions are stable for up to 1 month at -20°C. After thawing, discard any unused portion.

其他说明

Colleluori, D.M., and Ash, D.E. 2001. Biochemistry40, 9356.
Kim, N.N., et al. 2001. Biochemistry40, 2678.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C5H12BNO4S · xHCl
分子量193.03 (free base basis)

产品性质

质量水平100
测定≥97% (NMR)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
protect from light
颜色 white
溶解性water: 10 mg/mL
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3

Sigma-Aldrich

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