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Anti-SMRT Antibody, clone 1SM-1E7

品牌
Sigma-Aldrich
货号
04-1551
规格纯度
ascites fluid, clone 1SM-1E7, from mouse
参考价格
6526.19 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The Silencing mediator of retinoic acid & thyroid hormone receptor protein, commonly called the SMRT protein mediates the transcriptional repression of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription machinery. Consistent with this activity, this protein is known to form a large corepressor complex containing SIN3A/B and histone deacetylases HDAC1 and HDAC2. SMRT is also a component of the N-Cor repressor (nuclear receptor corepressor), a multi-subunit complex minimally composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. SMRT and nuclear receptor corepressor N-CoR are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

特异性

This antibody recognizes SMRT.

应用

Use Anti-SMRT Antibody, clone 1SM-1E7 (Mouse Monoclonal Antibody) validated in WB to detect SMRT also known as CTG repeat protein 26, Silencing mediator of retinoic acid & thyroid hormone receptor.

质量

Evaluated by Western Blot in human brain lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected SMRT on 10 µg of human brain lysate.

目标描述

~ 275 kDa

外形

Unpurified
Unpurified mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆1SM-1E7, monoclonal
species reactivityhuman, mouse, rat
technique(s)western blot: suitable
同位素/亚型IgG2aκ
NCBI登记号NP_001070729.1
UniProt登记号Q9Y618
运输dry ice
Gene Informationhuman ... NCOR2(9612), TRAC(28755)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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