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Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor® 488

品牌
Sigma-Aldrich
货号
FCMAB108A4
规格纯度
clone 5D11G5, from mouse, ALEXA FLUOR® 488
参考价格
4848.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

SMC (structural maintenance of chromosomes) proteins are Involved in chromosome cohesion during cell cycle and in DNA repair. ATM phosphorylates SMC1 on Ser957 and Ser966 both in vitro and in vivo. Phosphorylated SMC1 is part of the complex that functions as a downstream effector in both the ATM/NBS1 branch and the ATR/MSH2 branch of S-phase checkpoint.

特异性

Predicted to cross-react with xenopus and bovine based on sequence homology
Antibody recognizes SMC1 phosphorylolated at Ser957.

免疫原

Epitope: Phosphorylated at and around Ser957
KLH-conjugated, synthetic peptide corresponding to human SMC1 phosphorylated at Ser957

应用

Research Sub Category
Cell Cycle, DNA Replication & Repair
This Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor 488 is validated for use in WB, FC for the detection of phospho-SMC1 (Ser957).
Research Category
Epigenetics & Nuclear Function

Apoptosis & Cancer

质量

Evaluated by Flow Cytometry with Hela Cells

目标描述

150kDa Calculated

外形

Purified mouse monoclonal IgG1 conjugated to Alexa Flour 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein G Purified

储存及稳定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

分析说明

Control
HeLa Cells

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物ALEXA FLUOR® 488
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆5D11G5, monoclonal
species reactivityXenopus, human, bovine
technique(s)flow cytometry: suitable
western blot: suitable
同位素/亚型IgG1
NCBI登记号NM_006306
UniProt登记号Q14683
运输wet ice
Gene Informationhuman ... SMC1A(8243)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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