产品说明
一般描述
2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.
应用
2-Chloro-1-methylpyridinium iodide (CMPI) can be used as:
- A dehydrating agent for the conversion of various aldoximes to nitriles, and alcohols into alkyl thiocyanates.
- A cross-linking agent to fabricate biodegradable cross-linked hyaluronic acid film and gelatin membranes for biomedical applications.
- A condensing agent to synthesize various β-lactams from β-amino acids.
包装
10, 25, 100 g in glass bottle
基本信息
经验(实验)分子式 | C6H7ClIN |
分子量 | 255.48 |
Beilstein | 3572320 |
EC 号 | 238-288-7 |
MDL编号 | MFCD00011984 |
PubChem化学物质编号 | 24851856 |
NACRES | NA.22 |
产品性质
质量水平 | 200 |
测定 | 97% |
mp | 200 ℃ (dec.) (lit.) |
SMILES string | [I-].C[n+]1ccccc1Cl |
InChI | 1S/C6H7ClN.HI/c1-8-5-3-2-4-6(8)7;/h2-5H,1H3;1H/q+1;/p-1 |
InChI key | ABFPKTQEQNICFT-UHFFFAOYSA-M |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |