产品介绍：
产品说明
应用
次黄嘌呤是一种营养添加剂，适用于细菌、寄生虫(恶性疟原虫)和动物细胞等多种细胞培养应用。 次黄嘌呤是杂交瘤技术所用选择培养基的组分。
Hypoxanthine has been used:
- to gavage mice and to evaluate the activity of xanthine oxidase (XO) in pasteurized whole milk in vivo in potassium oxonate (PO) -induced mouse model of hyperuricemia
- as a supplement in Iscove′s modified Dulbecco′s medium (IMDM) medium to cultivate in-vitro cell line (EL-1 cells)
- as a pure standard for the quantification of hypoxanthine in vitreous fluid sample using high-performance liquid chromatography-ultra-violet (HPLC-UV) for the estimation of post-mortem interval
包装
1, 5, 25, 100 g in poly bottle
生化/生理作用
Hypoxanthine acts as an intermediate in purine metabolism. It elicits a vital role as a 5′-base of the anticodon in a few transfer-RNAs. Though similar to guanine (Gua), it is devoid of the exocyclic amino group at C(2) position. It may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases.
基本信息
| 经验(实验)分子式 | C5H4N4O |
| 分子量 | 136.11 |
| Beilstein | 5811 |
| EC 号 | 200-697-3 |
| MDL编号 | MFCD00005725 |
| PubChem化学物质编号 | 24895850 |
| NACRES | NA.51 |
产品性质
| 质量水平 | 300 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥99.0% |
| 形式 | powder |
| mp | >300 ℃ (lit.) |
| 溶解性 | formic acid: water (2:1): 50 mg/mL, clear to slightly hazy, colorless to yellow |
| SMILES string | O=C1NC=Nc2nc[nH]c12 |
| InChI | 1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10) |
| InChI key | FDGQSTZJBFJUBT-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
