产品介绍:
产品说明
应用
Pargyline hydrochloride has been used:
- as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training
- to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats,
- to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum
包装
1, 5 g in glass bottle
500 mg in glass bottle
生化/生理作用
Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.
选择性 MAO-B 抑制剂。
基本信息
线性分子式 | C6H5CH2N(CH3)CH2C≡CH·HCl |
分子量 | 195.69 |
Beilstein | 3699487 |
EC 号 | 206-175-1 |
MDL编号 | MFCD00012492 |
PubChem化学物质编号 | 24278153 |
NACRES | NA.77 |
产品性质
质量水平 | 200 |
生物来源 | synthetic |
测定 | 98% (TLC) |
形式 | powder or crystals |
mp | 160-163 ℃ (lit.) |
溶解性 | water: 50 mg/mL, clear, colorless to faintly yellow |
储存温度 | −20℃ |
SMILES string | Cl[H].CN(CC#C)Cc1ccccc1 |
InChI | 1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H |
InChI key | BCXCABRDBBWWGY-UHFFFAOYSA-N |
Gene Information | human ... MAOA(4128), MAOB(4129) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P310 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |