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SB-MDR1-Hi5-PREDEASY-ATPase kit

SB-MDR1-Hi5-PREDEASY-ATPase试剂盒

品牌
Sigma-Aldrich
货号
SBPE01
规格纯度
membrane based kit for Human MDR1 ATPase Transport Assays
参考价格
8016.22 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDEASY ATPase Assay Kit provides everything necessary to conduct ATPase activation and inhibition assays to better understand the nature of the interaction between a compound and the transporter. By measuring ATPase activity, both activation and inhibition of transporters can be investigated.

应用

SOLVO′s PREDEASY ATPase Assay Kit is a unique product for measuring the ATPase-dependent drug - ABC membrane transporter interaction in a convenient, "ready-to-assay" package. The ATPase assay is an in vitro membrane assay designed to indicate the nature of the interaction between the compound and the transporter. By measuring ATPase activity, both activation and inhibition of transporters can be investigated using membranes from baculovirus-infected insect cells or mammalian cell membranes containing high levels of human or rodent wild-type transporters. ABC transporters mediate the transport of substrates against a concentration gradient using energy derived from ATP hydrolysis, which is proportional to the transporter activity and could easily be detected with a colorimetric method.
PREDIVEZTM PREDEASY Kits contain all reagents (chemicals) and solutions necessary to conduct ATPase activation and inhibition assays. You only have to add water. Each kit comes with a CD that includes the assay protocol, data sheet, SDS, electronic data processing, evaluation templates and the reference data. The recommended layout allows activation and inhibition measurements in duplicates for 8 concentrations of the test article on one 96-well plate with all of the relevant controls.
PREDEASY ATPase Assay Kits are available for 3 and 10 plates for the transporters recommended by the FDA and the EMA.

外形

Supplied as frozen membrane vesicles, containing 5 mg/ml membrane protein, labeled with volume, catalog number (transporter), date of production, protocols and necessary reagents sufficient for the analysis of 3 or 10, 96-well plates.

法律信息

Distributed for SOLVO Biotechnology, Inc.
6538 is a trademark of American Type Culture Collection
PREDEASY is a trademark of Solvo Biotechnology

产品性质

重组expressed in insect cells
UniProt登记号P08183
运输dry ice
储存温度−70℃
Gene Informationhuman ... ABCB1(5243)

安全信息

象形图GHS02GHS05GHS07GHS08
警示用语:Danger
危险声明H226 - H290 - H314 - H335 - H350 - H412
预防措施声明P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
危险分类Aquatic Chronic 3 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
靶器官Respiratory system
储存分类代码3 - Flammable liquids
WGKWGK 3

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