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Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate

Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate

品牌
Sigma-Aldrich
CAS
93602-66-5
货号
A166
规格纯度
≥98% (HPLC), solid
参考价格
2523.26 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

1, 5, 10 mg in glass bottle

生化/生理作用

Sp-Diastereomer of adenosine 3′,5′-cyclic monophosphorothioate is a potent, membrane-permeable activator of cAMP dependent protein kinase I and II that mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases; exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP.

基本信息

经验(实验)分子式C10H11N5O5PS · C6H16N · xH2O
分子量446.46 (anhydrous basis)
MDL编号MFCD01459901
PubChem化学物质编号24890576
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
旋光性[α]22/D −25.43°, c = 0.99 in H2O(lit.)
颜色 white
溶解性H2O: soluble
web metadata keyword.defaultSp-3′,5′-cAMPS; A166; cAMPS-Sp; Sp-cAMPS; Adenosine 3′,5′-Cyclic-monophosphothioate, Sp-Isomer; phosphothioate; cAMP analogue; axial exocyclic; diastereomer; stereoselective agonist; stereoselective antagonist; camp dependent kinase; camp dependent protein kinase; forskolin; DBcAMP; dibutyryl
储存温度−20℃
SMILES stringCCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O
InChI1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21+;/m1./s1
InChI keyOXIPZMKSNMRTIV-BIQAKYJPSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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