产品说明
应用
Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons.
包装
1, 5 g in poly bottle
生化/生理作用
H1 histamine receptor antagonist.
特点和优势
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
制备说明
Triprolidine hydrochloride is soluble in water at 50 mg/ml and yields a clear, colorless to yellow solution. It is also soluble in alcohol (1 in 1.5 of solvent) and chloroform (1 in less than 1 of solvent).
基本信息
| 经验(实验)分子式 | C19H22N2 · HCl |
| 分子量 | 314.85 |
| MDL编号 | MFCD00039044 |
| PubChem化学物质编号 | 24277808 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥99% |
| 溶解性 | alcohol: soluble 1 in 1.5 of solvent chloroform: soluble 1 in less than 1 of solvent H2O: soluble 50 mg/mL, clear, colorless to yellow |
| 创始人 | GlaxoSmithKline |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C=C1)=CC=C1/C(C2=NC=CC=C2)=C\CN3CCCC3.Cl |
| InChI | 1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+; |
| InChI key | WYUYEJNGHIOFOC-NWBUNABESA-N |
| Gene Information | human ... HRH1(3269) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
