产品说明
应用
Gallamine triethiodide has been used:
- as a relaxant for measuring spinal trigeminal nucleus recordings from single neurons.
- as an antagonist in neuroblastoma cells as M2 receptor
- to reduce eye movement during retinal surgery in rat
包装
5, 25 g in poly bottle
生化/生理作用
Gallamine triethiodide has anti-muscarinic effect. It is a competitive antagonist for the muscarinic receptor. Gallamine is regarded as neuromuscular blocking agent.
Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase.
特点和优势
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
吸湿
基本信息
| 经验(实验)分子式 | C30H60I3N3O3 |
| 分子量 | 891.53 |
| EC 号 | 200-605-1 |
| MDL编号 | MFCD00011832 |
| PubChem化学物质编号 | 24277837 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| mp | 235 ℃ (dec.) (lit.) |
| 溶解性 | H2O: 100 mg/mL ethanol: soluble |
| 储存温度 | 2-8℃ |
| SMILES string | [I-].[I-].[I-].CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC |
| InChI | 1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9H3;3*1H/q+3;;;/p-3 |
| InChI key | REEUVFCVXKWOFE-UHFFFAOYSA-K |
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P301 + P312 + P330 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
