产品说明
一般描述
Caseins constitute 80% of the total milk proteins in the cow. κ-Casein is one of the major allergens in cow milk. It is a glycosylated protein comprising galactose, galactosamine, and sialic acid. It exists as tri- or tetrasaccharides and occurs in different isoforms based on the number of oligosaccharides attached to it. κ-Casein has a hydrophobic N-terminus and a hydrophilic C-terminus region.
应用
κ-Casein from bovine milk has been used:
- as a standard to quantify the casein concentration and to evaluate the ability of the bacterial strain to hydrolyze caseins released by HM Mozzarella
- in LPS-depleted cow′s milk protein preparation for lymphoproliferation assay
- as standard to quantify κ-casein concentration in skimmed milk samples by reversed-phase high-performance liquid chromatography (RP-HPLC)
包装
100, 250 mg in poly bottle
1 g in poly bottle
生化/生理作用
κ-Casein from bovine milk is an immunoglobulin E (IgE)-binding epitope belonging to the casein phosphoprotein family. κ-Casein is important to the electrostatic and steric stabilization of casein micelles suspensions. It resists calcium precipitation and therefore, stabilizes other caseins. κ-Casein has been a target of research for creating low-phenylalanine milk through gene modification, which is important for patients suffering from metabolic diseases such as phenylketonuria (PKU).
基本信息
EC 号 | 232-555-1 |
MDL编号 | MFCD00081481 |
NACRES | NA.61 |
产品性质
质量水平 | 200 |
生物来源 | bovine milk |
测定 | ≥70% (PAGE) |
形式 | lyophilized powder |
technique(s) | isoelectric focusing (IEF): suitable |
储存温度 | −20℃ |
Gene Information | cow ... MKCAS(100531419), MKCASP(105755569) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |