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Anti-Microtubule-Associated Proteins (MAPs) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
M7273
规格纯度
whole antiserum
参考价格
5549.05 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Microtubule-associated protein 2 (MAP2) is a neuronal protein. It belongs to the MAP2/Tau family. This gene is located to human chromosome 2q34-q35. MAP2 is present in neurons. MAP2 is the major microtubule-associated protein of brain tissue. There are two major classes of heat stable MAPs; two are similarly sized with apparent molecular weights of 280kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70kDa (MAP2c).

特异性

Reacts with the two major classes of heat stable MAPs (MAP2 and τ). Does not react with MAP1 or tubulin.

免疫原

heat stable MAPs prepared from bovine brain.

应用

Anti-Microtubule-Associated Proteins (MAPs) antibody produced in rabbit has been used in:

  • immunofluorescent labelling
  • immunohistochemistry
  • immunoprecipitation
  • immunofluorescence staining
  • western blotting

生化/生理作用

Microtubule-associated protein 2 (MAP2) interacts with microtubules to maintain the structure of dendrites. It plays a major role in supporting the actin cytoskeleton in spines, binding and nucleating filamentous actin (f-actin) to modulate spine morphology. Microtubules function as structural and mobility elements in mitosis, intracellular transport, flagellar movement and in the cytoskeleton.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00162605

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式whole antiserum
antibody product typeprimary antibodies
克隆polyclonal
包含15 mM sodium azide
species reactivitymammals
technique(s)western blot: 1:200
UniProt登记号P10636
运输dry ice
储存温度−20℃
Gene Informationhuman ... MAP2(4133), MAPT(4137)
mouse ... Mapt(17762), Mtap2(17756)
rat ... Map2(25595), Mapt(29477)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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