产品说明
Amino Acid Sequence
Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val
一般描述
The peptide represents amino acids 26-35 of MART-1 protein that is the melanoma antigen recognized by T cells. This peptide mimics the natural epitope that is presented by T cells in humans with reactivity to melanoma cells.
Melanoma-associated antigen recognized by T cells-1 (MART-1), also known as Melan-A, is encoded by the gene mapped to human chromosome 9p24.1. The encoded protein is a hydrophobic transmembrane protein. MART-1 is mainly expressed in skin and retinae melanocytes.
生化/生理作用
Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma.
外形
Lyophilized from 0.1% aqueous TFA
其他说明
Lyophilized from 0.1% TFA in H2O
基本信息
| NACRES | NA.32 |
产品性质
| 形式 | lyophilized powder |
| 质量水平 | 200 |
| 颜色 | white |
| 溶解性 | water, double-distilled: soluble |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
