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Caspase-3 Inhibitor II-CAS 210344-95-9-Calbiochem

品牌
Sigma-Aldrich
CAS
210344-95-9
货号
264155
规格纯度
The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
参考价格
1903.37 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/75 µl) solution of Z-DEVD-FMK (Cat. No. 264156) in DMSO is also available.
A potent, cell-permeable and irreversible inhibitor of CPP-32/apopain, a member of the ICE/CED-3 family of cysteine proteases.

包装

1 mg in Plastic ampoule
250 μg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
caspase-3, caspase-6, caspase-7, caspase-8, caspase-10

警告

Toxicity: Standard Handling (A)

序列

Z-Asp(OCH₃)-Glu(OCH₃)-Val-Asp(OCH₃)-FMK

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Masuda, Y., et al. 1997. Biochem. Biophys. Res. Commun. 234, 641.
Nicholson, D.W. 1996. Nature Biotech. 14, 297.
Schlegel, J., et al. 1996. J. Biol. Chem. 271, 1841.
Nicholson, D.W., et al. 1995. Nature 376, 37.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C30H41FN4O12
分子量668.66

产品性质

质量水平200
测定≥90% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated
颜色 white to slightly brown
溶解性DMSO: 5 mg/mL
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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